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2016

 

    2016

  • notavailable.pngBelyy A, Levanova N, Tabakova I, Rospert S, Belyi Y (2016). Ribosomal Protein Rps26 Influences 80S Ribosome Assembly in Saccharomyces cerevisiaemSphere 1

  • notavailable.pngZhang Y, Schaffer T, Wolfle T, Fitzke E, Thiel G, Rospert S (2016). Cotranslational intersection between the SRP and GET targeting pathways to the ER of Saccharomyces cerevisiae. Mol Cell Biol36: 2374-2383

  • notavailable.pngHübscher V, Mudholkar K, Chiabudini M, Fitzke E, Wölfle T, Pfeifer D, Drepper F, Warscheid B, Rospert S (2016) . The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae. Nucleic Acids Res44: 5629-5645.

  • notavailable.pngGumiero A, Conz C, Gesé GV, Zhang Y, Weyer FA, Lapouge K, Kappes J, von Plehwe U, Schermann G, Fitzke E, Wölfle T, Fischer T, Rospert* S, Sinning* I (2016). Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun7: 13563 (* co-corresponding)

  • notavailable.png Tholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, Stickeler E, Rospert S, Reinheckel T (2015). Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. J Biol Chem 290: 15758-15769

     

  • notavailable.pngEllenrieder L, Opalinski L, Becker L, Krüger V, Mirus O, Straub SP, Ebell K, Flinner N, Stiller SB, Guiard B, Meisinger C., Wiedemann N, Schleiff E, Wagner R, Pfanner N, Becker T (2016).Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10.Nat. Commun. 7, 13021.

     

  • download.pngChatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, Böttinger L, Mårtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar, A. (2016). MOF acetyl transferase regulates transcription and respiration in mitochondria. Cell 167, 722-738.

     

  • notavailable.pngSchuler MH, Di Bartolomeo F, Mårtensson CU, Daum G, Becker T (2016). Phosphatidylcholine affects inner membrane protein translocases of mitochondria. J Biol Chem291, 18718-18729.

     

  • notavailable.pngMüller CS, Bildl, W, Haupt A, Ellenrieder L, Becker T, Hunte C, Fakler B, Schulte U (2016). Cryo-slicing BN-MS – a novel technology for high-resolution complexome profiling. Mol. Cell. Proteomics 15, 669-681.

     

  • download.pngChlamydas S, Holz H, Samata M, Chelmicki T, Goergiev P, Pelechano V, Dündar F, Dasmeh P, Mittler G, Tavares Cadete F, Ramírez F, Conrad T, Wei W, Raja S, Manke T, Luscombe NM, Steinmetz LM and Akhtar A (2016).Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation. Nature Structural and Molecular Biology 23, 580-589.

     

  • download.pngSheikh BN, Bechtel-Walz W, Lucci J, Karpiuk O, Hild I, Hartleben B, Vornweg J, Diehl S, Sahyoun A, Stehle T, Voss AK, Thomas T, Kretz O, Manke T, Huber TB, Bhardwaj V, Akhtar A (2016). MOF maintains Transcriptional Programs regulating Cellular Stress Response. Oncogene 35(21), 2698-710.

     

  • notavailable.png Levit-Zerdoun E, Becker M, Pohlmeyer R, Wilhelm I, Maity PC, Rajewsky K, Reth M, Hobeika E (2016). Survival of Iga-deficient mature B cells requires BAFF-R function. J Immunol 196 (3):2348-2360.

     

  • notavailable.png Volkmann C, Brings N, Becker M, Hobeika E, Yang J, Reth M. (2016). Molecular requirements of the B cell antigen receptor for sensing monovalent antigens. EMBO J 35 (21):2371-2381.

     

  • notavailable.png L`Kao W, Kleinschroth T, Nitschke W, Baymann F, Neehaul Y, Hellwig P, Richers S, Vonck J, Bott M, Hunte C (2016). The actinobacterial obligate respiratory supercomplex from Corynebacterium glutamicum. Biochim. Biophys. Acta 1857, 1705-1714.

     

  • notavailable.png Wirth C, Brandt U, Hunte C#, Zickermann V# (2016). Structure and function of mitochondrial complex I. Biochim. Biophys. Acta 1857, 902-914. #corresponding author.

     

  • notavailable.png Duteil, D., Tosic, M., Lausecker, F., Nenseth, H. Z., Müller, J. M., Urban, S., Willmann, W., Petroll, K., Messaddeq, N., Arrigoni, L., Manke, T., Kornfeld, J.-W., Brüning, J.C., Zagoriy, V., Meret, M., Dengjel, J., Kanouni, T. and Schüle, R. (2016). Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue.Biochim. Biophys. Acta17, 1008-1021.

     

  • notavailable.png Rohde, M., Sievers, E., Janzer, A., Willmann, D., Egert, A., Schorle, H., Schüle R. and Kirfel, J. (2016). SOverexpression of histone demethylase Fbxl10 leads to enhanced migration in mouse embryonic fibroblasts.Exp Cell Res348, 123-131.

     

  • notavailable.png Robaa, D., Wagner, T., Luise, C., Carlino, L., McMillan, J., Flaig, R., Schüle, R., Jung, M.and Sippl, W. (2016). Identification and Structure-Activity Relationship Studies of Small-Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1.ChemMedChemdoi: 10.1002/cmdc.201600362.

     

  • notavailable.pngOstrovskyi, D., Rumpf, T., Eib, J., Lumbroso, A., Slynko, I., Klaeger, S., Heinzlmeir, S,. Forster M, Gehringer M, Pfaffenrot E, Bauer SM, Schmidtkunz K, Wenzler S, Metzger E, Kuster, B., Laufer, S., Schüle, R., Sippl, W., Breit, B. and Jung. M. (2016). Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1). Future Med Chem. 13,1537-1551.

     

  • notavailable.png Morera, L., Roatsch, M., Fürst, M. C. D., Hoffmann, I., Senger,J., Hau, M., Franz, H., Schüle, R., Heinrich, M. R. and Jung, M. (2016). 4-Biphenylalanine- and 3-Phenyltyrosine-Derived Hydroxamic Acids as Inhibitors of the JumonjiC Domain-Containing Histone Demethylase KDM4A. ChemMedChem 1doi: 10.1002/cmdc.201600218.

     

  • notavailable.png Slynko, I., Schmidtkunz, K., Rumpf, T., Klaeger, S., Heinzlmeir, S., Najjar, A., Metzger, E., Kuster, B., Schüle, R., Jung, M. and Sippl, W. (2016). Identification of highly potent PRK1 inhibitors by virtual screening, binding free energy rescoring and in vitro testing. ChemMedChem.doi: 10.1002/cmdc.201600284.

     

  • notavailable.png Wu, X., Schneider, N., Platen, A., Mitra, I., Blazek, M., Zengerle, R., Schüle, R. and Meier, M. (2016). In situ characterization of the mTORC1 during adipogenesis of human adult stem cells on chip. Proc. Natl. Acad. Sci. USA113, doi: 10.1073/pnas.1601207113.

     

  • notavailable.png Hügle, M., Lucas, X., Weitzel, G., Ostrovskyi, D., Breit, B., Gerhardt, S., Schmidtkunz, K., Jung, M., Schüle, R., Einsle, O., Günther, S. and Wohlwend, D. (2016). SPreparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes. Data Brief.7, 1370-1374.

     

  • notavailable.png Roatsch, M., Robaa, D., Pippel, M., Nettleship, J.E., Reddivari, Y., Bird, L.E., Hoffmann, I., Franz, H., Owens, R.J., Schüle, R., Flaig, R., Sippl, W. and Jung, M. (2016). Substituted 2-(2-aminopyrimidin-4-yl)pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases. Future Med. Chem. 13, 1553-71.

     

  • notavailable.png Wagner, T., Greschik, H., Burgahn, T., Schmidtkunz, K., Schott, A.K., McMillan, J., Baranauskiene, L., Yan, X., Fedorov, O., Jian, J., Oppermann, U., Matulis, D., Schüle, R. and Jung, M. (2016). Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform. Nucleic Acids Res. 441doi: 10.1093/nar/gkw089

     

  • notavailable.png Ancelin, K., Syx, L., Borensztein, M., Ranisavljevic, N., Vassilev, I., Briseno-Roa, L., Liu, T., Metzger, E., Servant, N., Barillot, E., Chen, C-J., Schüle, R. and Heard, E. (2016). Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. eLIFE pii: e08851.

     

  • notavailable.pngMetzger, E., Willmann, D., McMillan, J., Forne, I., Petroll, K., Metzger, P., Gerhardt, S., Maessenhausen, A., Schott, A-K., Espejo, A., Eberlin, A., Wohlwend, D., Schüle, K.M., Schleicher, M., Perner, S., Bedford, M.T., Jung, M., Dengjel, J., Flaig, R., Imhof, A., Einsle, O. and Schüle, R. (2016). SAssembly of methylated KDM1 and CHD1 drives AR-dependent transcription and translocation. Nat. Struct. Mol. Biol. 23, 132-139.

     

  • notavailable.pngBausewein D, Engel J, Jank T, Schoedl M, Strahl S (2016). Functional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1.J Biol Chem. 291(34):18006-15.

     

  • notavailable.pngJank T, Lang AE, Aktories K (2016). Rho-modifying bacterial protein toxins from Photorhabdus species.Toxicon 116:17-22, Review.

     


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