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2017

 

    2017

  • notavailable.pngHübscher V, Mudholkar K, Rospert S (2017). The yeast Hsp70 homolog Ssb: a chaperone for general de novo protein folding and a nanny for specific intrinsically disordered protein domains. Curr Genet 63: 9-13

  • notavailable.pngJank T, Belyi Y, Wirth C, Rospert S, Hu Z, Dengjel J, Tzivelekidis T, Andersen GR, Hunte C, Schlosser A, Aktories K (2017). Protein glutaminylation is a yeast-specific posttranslational modification of elongation factor 1A. J Biol Chem 292:16014-16023

  • notavailable.pngZhang Y, Sinning I, Rospert S (2017). Two chaperones locked in an embrace: Structure and function of the ribosome-associated complex RAC. Nat Struct Mol Biol 24:611-619.

  • notavailable.pngMudholkar K, Fitzke E, Prinz C, Mayer MP, Rospert S (2017). The Hsp70 homolog Ssb affects ribosome biogenesis via the TORC1-Sch9 signaling pathway. Nat Commun8: 937

  • notavailable.pngKrüger V, Becker T, Becker L, Montilla-Martinez M, Ellenrieder L, Vögtle FN, Meyer H, Ryan M, Wiedemann N, Warscheid B, Pfanner N, Wagner R, Meisinger C (2017). Identification of new channels by systematic analysis of the mitochondrial outer membrane. J. Cell Biol. 216, 3485-3495

     

  • notavailable.pngMårtensson CU, Becker T (2017). Acylglycerol Kinase: Mitochondrial protein transport meets lipid biosynthesis. Trends Cell Biol. 27, 700-702

     

  • notavailable.pngEllenrieder L, Rampelt H, Becker T (2017). Connection of protein transport and organelle contact sites in mitochondria. J Mol Biol 429, 2148-2160.

     

  • notavailable.pngMårtensson CU, Doan KN, Becker T (2017). Effects of lipids on mitochondrial functions. Biochim Biophys Acta. 182, 102-113

     

  • notavailable.pngAktas T, Ilik IA, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G., Manke T, Backofen R, Akhtar A (2017). DHX9 suppresses RNA processing defects originating from Alu invasion of the human genome. Nature544, 115-119.

     

  • notavailable.pngIlik IA, Maticzka D, Georgiev P, Gutierrez N., Backofen R, Akhtar A (2017). A mutually exclusive stem-loop arrangement in roX2 RNA is essential for X-chromosome regulation in Drosophila. Genes & Development 31, 1973-1987.

     

  • notavailable.pngMinguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Poszo, MA (2017). Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance. Nat Immunol 18 (10): 1150-1159.

     

  • notavailable.pngDolezal E, Infantino S, Drepper F, Börsig T, Singh A, Wossning T, Fiala GJ, Minguet S, Warscheid B, Tarlinton DM, Jumaa H, Medgeysi D, Reth M (2017). The BTG2-PRMT2 module limits pre-B cell expansion by regulating the CDK4-Cyclin-D3 complex. Nat Immunol 118(8): 911-920.

     

  • notavailable.pngBecker M, Hobeika E, Jumaa H, Reth M, Maity PC (2017). CXCR4 signaling and function require the expression of the IgD-class B-cell anitgen receptor. Proc Natl Acad Sci USA 114(20): 5231-5236.

     

  • notavailable.pngMetzger E, Stepputtis SS, Strietz J, Preca BT, Urban S, Willmann D, Allen A, Zenk F, Iovino N, Bronsert P, Proske A, Follo M, Boerries M, Stickeler E, Xu J, Wallace MB, Stafford JA, Kanouni T, Maurer J and Schüle R (2017) KDM4 Inhibition Targets Breast Cancer Stem-like Cells. Cancer Res 77(21); 5900-12

     

  • notavailable.pngDuteil, D., Tosic, M. and Schüle, R. (2017). Lsd1, a metabolic sensor of environment requirements that prevents adipose tissue from aging. Adipocyte 2017 doi: 10.1080/21623945.2017.1345831.

     

  • notavailable.pngHaydn, T., Metzger, E., Schüle, R. and Fulda, S. (2017). CConcomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells. Cell Death Dis 8, e2879; doi: 10.1038/cddis.2017.239.

     

  • notavailable.pngDuteil, D., Tosic, M., Willmann, W., Georgiadi, A., Kanouni, T. and Schüle, R. (2017). Lsd1 prevents age-programed loss of beige adipocytes Proc. Natl. Acad. Sci. USA 114, 5265-5270.

     

  • notavailable.pngGreschik, H., Schüle, R. and Günther, T. (2017). Selective targeting of epigenetic reader domains. Expert Opin Drug Discov. 5, 449-463.

     

  • notavailable.pngErnst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H (2017). Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells. Sci Rep. 2;7(1):2724

     

  • notavailable.pngScionti, I., Hayashi, S., Mouradian, S., Girard, E., Esteves de Lima, J., Morel, V., Simonet, T., Wurmser, M., Maire, P., Ancelin, K., Metzger, E., Schüle, R., Goillot, E., Relaix, F. and Schaeffer. L. (2017). LSD1 controls timely MyoD expression via MyoD core enhancer transcription. . Cell Rep.18, 1996-2006.

     

  • notavailable.pngCastex, J., Willmann, D., Kanouni, T., Arrigoni, L., Li, Y., Friedrich, M., Schleicher, M., Wöhrle, S., Pearson, M., Kraut, N., Méret, M., Manke, T., Metzger, E., Schüle, R. and Günther, T. (2017). Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4. Cell Death Dis. 8, e2631.

     

  • notavailable.pngMoreno-Juan, V., Filipchuk, A., Antón-Bolaños, N., Mezzera, C., Gezelius, H., Andrés, B., Rodriguez-Malmierca, L., Susín, R., Schaad, O., Iwasato, T., Schüle, R., Rutlin, M., Nelson, S., Ducret, S., Valdeolmillos, M., Rijli. F.M. and López-Bendito, G. (2017). Prenatal thalamic waves regulate cortical area size priorto sensory processing. Nat. Commun. 8, 14172.

     

  • notavailable.pngAktories K, Schwan C, Jank T (2017). Clostridium difficile Toxin Biology. Annu Rev Microbiol. 71:281-307

     

  • notavailable.pngHessenberger, M., Zerbes, R.M., Rampelt, H., Kunz, S., Xavier, A.H., Purfürst, B., Lilie, H., Pfanner, N., van der Laan, M., and Daumke, O. (2017). Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctions. Nat. Commun. 8, 15258.

     

  • notavailable.pngMorgenstern, M., Stiller, S.B., Lübbert, P., Peikert, C.D., Dannenmaier, S., Drepper, F., Weill, U., Höß, P., Feuerstein, R., Gebert, M., Bohnert, M., van der Laan, M., Schuldiner, M., Schütze, C., Oeljeklaus, S., Pfanner, N., Wiedemann, N., and Warscheid, B. (2017). Definition of a high-confidence mitochondrial proteome at quantitative scale. Cell Rep. 19, 2836-2852.

     

  • notavailable.pngRampelt, H., Bohnert, M., Zerbes, R.M., Horvath, S.E, Warscheid, B., Pfanner, N., and van der Laan, M. (2017). Mic10, a core subunit of the mitochondrial contact site and cristae organizing system, interacts with the dimeric F1Fo-ATP synthase. J. Mol. Biol. 429, 1162-1170.

     

  • notavailable.pngRampelt, H., Zerbes, R.M., van der Laan, M., and Pfanner, N. (2017). Role of the mitochondrial contact site and cristae organizing system in membrane architecture and dynamics. Biochim. Biophys. Acta 1864, 737-746.

     

  • notavailable.pngWiedemann, N., and Pfanner, N. (2017). Mitochondrial machineries for protein import and assembly. Annu. Rev. Biochem. 86, 685-714.

     

  • notavailable.pngUlfig, A., Fröbel, J., Lausberg, F., Blümmel, A.S., Heide, A.K., Müller, M. & Freudl, R. The h-region of twin-arginine signal peptides supports productive binding of bacterial Tat precursor proteins to the TatBC receptor complex (2017).J. Biol. Chem. 292, 10865-10882.

     

  • notavailable.pngBlümmel, A.S., Drepper, F., Knapp, B., Eimer, E., Warscheid, B., Müller, M. & Fröbel, J. Structural features of the TatC membrane protein that determine docking and insertion of a twin-arginine signal peptide. (2017).J. Biol. Chem. 292, 21320-21329.

     


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