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2015

 

    2015

  • notavailable.pngZickermann V, Christophe Wirth C, Nasiri H, Siegmund K, Schwalbe H, Hunte C, Ulrich Brandt U (2015) Mechanistic Insight from the Crystal Structure of Mitochondrial Complex, Science 347, 44-49

  • notavailable.pngBanerjee A, Tsai CL, Chaudhury P, Tripp P, Arvai AS, Ishida JP,Tainer JA, Albers SV (2015). FlaF is a β-sandwich protein that anchors the archaellum in the archaeal cell envelope by binding the S-layer protein. Structure, in press

  • notavailable.pngMaity PC, Yang J, Klaesener K, Reth M. (2015). The nanoscale organization of the B lymphocyte membrane. Biochim Biophys Acta 1853(4): 830-840.

  • notavailable.pngHobeika E, Levit-Zerdoun E, Anastasopoulou V, Pohlmeyer R, Altmeier S, Alsadeq A, Dobenecker MW, Pelanda R, Reth M. (2015). CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk. EMBO J. 34(7):925-39

  • notavailable.pngAlarcon B, Reth M, Schamel W. (2015). Preface to special issue on nanoscale membrane organisations. Biochim Biophys Acta 1853(4): 765-766.

  • notavailable.pngBusch K, Klapproth K, Barile M, Flossdorf M, Holland-Letz T, Schlenner SM, Reth M, Höfer T, Rodewald HR. (2015). Fundamental properties of unperturbed haematopoiesis from stem cells in vivo. Nature 518(7540): 542-546.

  • notavailable.pngThien A, Prentzell MT, Holzwarth B, Kläsener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K. (2015). TSC1 Activates TGF-beta-Smad2/3 Signaling in Growth Arrest and Epithelial-to-Mesenchymal Transition. Dev Cell 32(5): 617-630.

  • notavailable.pngBohnert, M., Zerbes, R.M., Davies, K.M., Mühleip, A.W., Rampelt, H., Horvath, S.E., Boenke, T., Kram A., Perschil, I., Veenhuis, M., Kühlbrandt, W., van der Klei, I.J., Pfanner, N., and van der Laan, M. (2015). Central role of Mic10 in the mitochondrial contact site and cristae organizing system. Cell Metab. 21, 747-755.

  • notavailable.pngChen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman, CL, Melnick A, Mignon LL, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Clifford AL & Müschen M (2015). Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature , 521(7552):357-61

  • notavailable.pngBlümmel AS, Haag LA, Eimer E, Müller M, Fröbel J (2015) Initial assembly steps of a translocase for folded proteins. Nat Commun. 6:7234.

     

  • notavailable.png Boettinger L, Oeljeklaus S, Guiard B, Rospert S, Warscheid B, Becker T (2015). SThe mitochondrial heat shock protein 70 (Hsp70) and Hsp10 cooperate in the formation of Hsp60 complexes. J Biol Chem 290: 11611-11622

     

  • notavailable.pngTholen M, Wolanski J, Stolze B, Chiabudini M, Gajda M, Bronsert P, Stickeler E, Rospert S, Reinheckel T (2015). Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. J Biol Chem 290: 15758-15769

     

  • notavailable.png Wenz LS, Ellenrieder L, Qiu J, Bohnert M., Zufall N., van der Laan M., Pfanner N., Wiedemann N,Becker, T (2015). Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting -barrel biogenesis.J. Cell. Biol. 210, 1047-1054.

     

  • notavailable.pngSchuler MH, Di Bartolomeo F, Böttinger L, Horvath SE, Wenz LS, Daum G Becker T (2015). Phosphatidylcholine affects the role of the sorting and assembly machinery in the biogenesis of mitochondrial beta-barrel proteins. J Biol Chem290, 26523-26532.

     

  • notavailable.pngBöttinger L, Oeljeklaus S, Guiard B, Rospert S, Warscheid B, Becker T (2015). The mitochondrial heat shock protein 70 (Hsp70) and Hsp10 cooperate in the formation of Hsp60 complexes. J. Biol. Chem. 290, 11611-11622.

     

  • notavailable.pngEllenrieder L, Mårtensson CU., Becker T (2015). Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Biol. Chem. 396, 1199-1213.

     

  • notavailable.pngWenz LS, Opalinski L, Wiedemann N., Becker, T. (2015). Cooperation of protein machineries in mitochondrial protein sorting. Biochim Biophys Acta. 1853, 1119-1129

     

  • download.pngKeller CI and Akhtar A (2015). The MSL complex: juggling RNA-protein interactions for dosage compensation and beyond. Current Opinion in Genetics & Development 31, 1-11.

     

  • download.pngRamirez F, Lingg T, Toscano S, Lam KC, Georgiev P, Chung HR, Lajoie B, de Wit E, Zhan Y, de Laat W, Dekker J, Manke T and Akhtar A (2015). High-affinity sites form an interaction network to facilitate spreading of the MSL complex across the X chromosome in Drosophila. Molecular Cell 60, 146-162.

     

  • download.pngMeunier S, Shvedunova M, Van Nhuong N, Avila L, Vernos I, Akhtar A (2015). An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis. Nature Communications6, doi:10.1038/ncomms8889.

     

  • notavailable.pngMir SH, Escher C, Kao WC, Birth D, Wirth C, Hunte C (2015). Generation of recombinant antibody fragments for membrane protein crystallization.Methods Enzym.557, 201-218.

     

  • notavailable.pngFedorov O., Castex J., Tallant C., Owen DR, Martin S, Aldeghi M, Monteiro O, Filippakopoulos P, Picaud S, Trzupek JD, Gerstenberger BS, Bountra C, Willmann D, Wells, C, Philpott M, Rogers C, Biggin PE, Brennan P, Bunnage ME, Schüle R, Günther T, Knapp S and Müller S (2015). Selective Targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cells maintenance.Science Adv. 1e1500723.

     

  • notavailable.pngRüger N, Roatsch M, Emmrich T, Franz H, Schüle R, Jung M and Link A. (2015). Tetrazolylhydrazides as selective fragment-like inhibitors of the JumonjiC domain-containing histone demethylase KDM4A.ChemMedChem10, 1875-1883..

     

  • notavailable.pngFranz H, Greschik H, Willmann D, Ozretić L, Jilg CA, Wardelmann E, Jung M, Buettner R and Schüle R (2015). The histone code reader SPIN1 controls RET signaling in liposarcoma. Oncotarget6, 4773-4489..

     

  • notavailable.pngWestphal P, Mauch C, Florin A, Czerwitzki J, Olligschläger N, Wodtke C, Schüle R, Büttner R and Friedrichs N. (2015). Enhanced FHL2 and TGF-β1 Expression Is Associated With Invasive Growth and Poor Survival in Malignant Melanomas. Am. J. Clin. Pathol. 143, 248-256.

     

  • notavailable.pngAl-Nomani L, Friedrichs J, Schüle R, Büttner R and Friedrichs N. (2015) . Tumoral expression of nuclear cofactor FHL2 is associated with lymphatic metastasis in sporadic but not in HNPCC-associated colorectal cancer. Pathol. Res. Pract.211, 171-174.

     

  • notavailable.pngKrönig M, Walter M, Drendel V, Werner M, Jilg CA, Richter AS, Backofen R, McGarry D, Follo M, Schultze-Seemann W and Schüle R (2015) . Cell type specific gene expression analysis of prostate needle biopsies resolves tumor tissue heterogeneity. Oncotarget6, 1302-1314.

     

  • notavailable.pngFriedrichs J, Fink D, Mauch C, Kindler K, Hartmann W, Schüle R, Buettner R and Friedrichs N (2015). TGF-β1-dependent induction and nuclear translocation of FHL2 promotes keratin expression in pilomatricoma. Virchows Arch. 466, 199-208.

     

  • notavailable.pngRönsch K, Jägle S, Rose K, Seidl M, Baumgartner F, Freihen V, Yousaf A, Metzger E, Lassmann S, Schüle R, Zeiser R, Michoel T and Hecht A (2015). SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer. Mol. Oncol. 9, 335-54.

     

  • notavailable.pngRBelyy A, Tabakova I, Lang AE, Jank T, Belyi Y, Aktories K (2015). Roles of Asp179 and Glu270 in ADP-Ribosylation of Actin by Clostridium perfringens Iota Toxin. PLoS One 10(12):e0145708.

     

  • notavailable.pngJank T, Belyi Y, Aktories K (2015). Bacterial glycosyltransferase toxins. Cell Microbiol. (12):1752-65.

     

  • notavailable.pngJank T, Eckerle S, Steinemann M, Trillhaase C, Schimpl M, Wiese S, van Aalten DM, Driever W, Aktories K (2015). Tyrosine glycosylation of Rho by Yersinia toxin impairs blastomere cell behaviour in zebrafish embryos. Nat Commun. 20;6:7807.

     

  • notavailable.pngJank T, Trillhaase C, Brozda N, Steinemann M, Schwan C, Süss R, Aktories K (2015). Intracellular plasma membrane guidance of Photorhabdus asymbiotica toxin is crucial for cell toxicity. FASEB J. (7):2789-802.

     

  • notavailable.pngShiota, T., Imai, K., Qiu, J., Hewitt, V.L., Tan, K., Shen, H.H., Sakiyama, N., Fukasawa, Y., Hayat, S., Kamiya, M., Elofsson, A., Tomii, K., Horton, P., Wiedemann, N., Pfanner, N., Lithgow, T., and Endo, T. (2015). Molecular architecture of the active mitochondrial protein gate. Science 349, 1544-1548.

     

  • notavailable.pngHorvath, S.E., Rampelt, H., Oeljeklaus, S., Warscheid, B., van der Laan, M., and Pfanner, N. (2015). Role of membrane contact sites in protein import into mitochondria.Protein Sci. 24, 277-297.

     

  • notavailable.pngBohnert, M., Pfanner, N., and van der Laan, M. (2015). Mitochondrial machineries for insertion of membrane proteins. Curr. Opin. Struct. Biol. 33, 92-102.

     

  • notavailable.pngEimer, E., Fröbel, J., Blümmel, A.S. & Müller, M. (2015) TatE as a Regular Constituent of Bacterial Twin-arginine Protein Translocases. J. Biol. Chem. 290, 29281-29289

     


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